My 7-Day Review of Density Structure Night Serum by QMS Medicosmetics

Could QMS Medicosmetics’ serum be the secret to firmer skin? I tried it out.
Updated on: April 1, 2025

Image courtesy of QMS Medicosmetics

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QMS Medicosmetics might not be the most familiar name on everyone’s lips, but it has certainly made a statement with its “Density Structure Night Serum.” The brand promises an innovative formula designed to work while you sleep, encouraging firmer-looking skin and a smooth, more even-toned finish. Over the past week, I put this serum to the test to see how it held up, and whether it’s truly worth the investment.

Note: This isn’t a paid or sponsored review, and all opinions shared here reflect my personal experience. Remember, skincare results can vary from person to person, so your experience may differ from mine.

What Is Density Structure Night Serum?

This product is a night serum, meaning it’s specifically formulated to be applied before bed and left on while you sleep. Night serums generally aim to provide nourishment and help with skin rejuvenation during the hours your skin is most receptive to active ingredients. In this case, the Density Structure Night Serum focuses on encouraging a firmer-looking complexion and smoother skin texture as you rest.

It’s described as suitable for all skin types and is designed to retexturise the skin for a more even tone. Powered by ingredients like hyaluronic acid and vitamin E, it seeks to keep the skin barrier supported while minimizing the look of fine lines and wrinkles. Those who want an intensive overnight product to complement their existing routine might see this as an option to consider, particularly if they pair it with the recommended Night Collagen.

Did It Work?

To put the serum to the ultimate test, my usual night cream was benched for a few days, very scientific, I know, and I used Density Structure Night Serum exclusively for seven nights. Application was hassle-free: just a small amount massaged into clean skin after my evening cleanse. On the first night, the product felt comfortable, not overly heavy, and seemed to absorb quickly. By midweek, I noticed my skin looked a bit smoother in the mornings, but I didn’t experience any dramatic transformations.

By the end of the seven days, my skin felt nicely hydrated and a hint firmer, especially around my cheek area, but the difference wasn’t exactly groundbreaking. Fine lines didn’t vanish, though they seemed slightly less obvious because my skin was well moisturized. I also didn’t witness any adverse reactions, such as redness or breakouts. Overall, there was a respectable improvement in texture, though I was still on the fence about whether it was enough to justify swapping out my regular product for the long term.

In terms of delivering on its promise of firmer, smoother-looking skin, it certainly did a decent job. However, while I can vouch that it works reasonably well, I’m not rushing to add it to my regular skincare rotation. It’s solid, but it didn’t quite win me over completely.

Density Structure Night Serum’s Main Ingredients Explained

When you scan the ingredients list for Density Structure Night Serum, it’s clear that QMS Medicosmetics intended this product to be deeply nourishing without feeling too heavy. The spotlight is on two notable powerhouses: hyaluronic acid (listed as Sodium Hyaluronate) and vitamin E (Tocopherol). Hyaluronic acid helps skin retain moisture and maintain elasticity, making your face look and feel more supple. Meanwhile, vitamin E targets free radicals to support overall skin health and resilience.

Another key ingredient is Orbignya Oleifera Seed Oil (often called Babassu Oil). It’s a lightweight oil that can help soften the skin and lock in hydration without leaving a greasy finish. Linoleic acid also appears on the label, an essential fatty acid that’s believed to help maintain a strong skin barrier. These hydrating and barrier-supporting components work together to give your skin a smoother texture over time.

As for whether it’s suitable for vegans or vegetarians, the formula doesn’t contain obvious animal-derived ingredients, though some elements like glycoproteins could be sourced in various ways. If you have strict dietary preferences, it might be worth double-checking with the brand to confirm how they source their glycoproteins and glycerin.

In terms of being comedogenic, meaning it could potentially clog pores and promote breakouts, none of the listed ingredients are typically flagged as major pore-cloggers. However, everyone’s skin can react differently, so it’s worth keeping an eye out if you’re prone to breakouts. Another detail worth noting is the presence of fragrance (Parfum) and BHT, which some people may prefer to avoid if they have sensitivities. Overall though, the formula is more moisturizing and barrier-supportive than problematic, and it seems crafted with a focus on helping skin look smoother and firmer by the time you wake up.

What I Liked/Didn’t Like

After a week of nightly use, I came away with a balanced view of what stood out and where this serum may fall short. Here’s a quick rundown:

What Works Well:

  • Absorbs quickly, leaving skin feeling hydrated without a heavy residue.
  • Helps soften and smooth skin texture, making fine lines appear less noticeable.
  • Works effectively as an overnight companion to other skincare steps, especially when paired with the recommended Night Collagen.

What to Consider:

  • Price may feel steep for those on a budget, given the results aren’t dramatically transformative.
  • Contains fragrance, which may not suit individuals who prefer scent-free formulas or have sensitivities.
  • While it does provide a nice boost of moisture, anyone seeking immediate or more dramatic firming might find it a bit subtle.

My Final Thoughts

Finding a good night treatment can feel like a never-ending quest, especially when so many brands promise the moon and stars in terms of instant firmness and magical transformation. After a fair try with QMS Medicosmetics Density Structure Night Serum, I’d say it’s a respectable pick for those seeking gentle overnight hydration that supports a slightly firmer and smoother complexion. However, if you’re someone who wants a more dramatic change in fine lines or a heavier-duty nighttime formula, you might find it a bit subtle. Having tested a fair share of night products over the years, I can confidently give this serum a 7/10, good, but not earth-shattering. I would still recommend it to a friend who’s looking for a mid-level night serum that keeps skin reasonably moisturized and balanced without weighing it down.

For those who love alternatives or simply want more options, I’ve also had hands-on experience with several other solid overnight products. One standout is the Nocturnal Revive Cream by Deascal, which is an excellent allrounder that covers all bases for virtually all skin types while keeping the price point friendlier. If you’re after an ultra-hydrating formula, the Water Sleeping Mask by LANEIGE delivers a refreshing surge of moisture without feeling heavy by morning. And for a bit of a luxe retexturizing effect, Advanced Night Restore by Medik8 is another one I’ve personally enjoyed, it offers an impressive balance of hydration and firmness that feels a touch more potent. Looking for an extra boost for very dull days? Confidence in Your Beauty Sleep by IT Cosmetics has given me noticeable results in plumping and smoothing, enough that it remains in my rotation.

Before slathering on any new product, remember to consider a few important points. Different ingredients can affect everyone’s complexion differently, and consistency in use is key, don’t expect permanent results if you only apply once a week. Also, do a small patch test, especially if your skin is prone to sensitivity. As with most skincare, the payoff takes time, and you’ll want to stick with it to see the full benefits. Happy (and careful) experimenting!

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