My 7-Day Review of Synactif Nighttime Moisturiser by Clé de Peau Beauté

Is Clé de Peau Beauté's Synactif Nighttime Moisturiser the secret to perfection? I tried it.
Updated on: April 1, 2025

Image courtesy of Clé de Peau Beauté

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Clé de Peau Beauté may or may not be on everyone’s radar, but it certainly carries a luxurious reputation within the skincare world. That said, its Synactif Nighttime Moisturiser, despite the mouthful of a name, promises a moisture-locking formula that’s meant to melt on and leave skin looking smooth and supple. The brand recommends using three pumps of product, spreading it evenly across the face, neck, and forehead , no spots left behind.

After a full week of nightly use, it’s safe to say there’s a lot worth discussing here, from the overall hydration levels to the claim of smoothing fine lines. Rest assured, this is not a paid or sponsored review. The thoughts and experiences shared are entirely my own, and while I’m giving it a solid 7/10, it’s worth noting that everyone’s skin reacts differently. Results can vary, but for me, this is how it performed.

What Is Synactif Nighttime Moisturiser?

Synactif Nighttime Moisturiser is, at its core, a night cream. These types of products are formulated to be worn while you sleep, when skin typically goes into a regenerative mode. The idea is that applying this moisturiser as the last step of an evening skincare routine helps lock in hydration and support overnight skin repair.

Synactif’s version, described as having a “rich formula,” is meant to deeply absorb, offering a hydrating sensation with each application. The brand suggests using three pumps, applying outwards on the face, and covering the neck and forehead. According to them, regular use may soften the visibility of fine lines around the eye area and encourage smoother, more resilient-looking skin.

Night creams in general are beneficial for those looking to maintain moisture levels, support the skin’s natural repair process, and potentially address concerns such as dryness or early signs of aging. While the exact effects vary, the goal is often to wake up with a refreshed, well-hydrated complexion.

Did It Work?

In a highly scientific move (or so it felt), I decided to put my usual night cream on pause for a full seven days to really see what this formula could do on its own. From the very first application, it felt silky and rich on the skin – not in a suffocating way, but more like a gentle blanket of hydration that promised good things. Three pumps were plenty to spread across my face, neck, and forehead without feeling the need for an extra dab here or there. Plenty of slip and a quick, surprisingly soft finish.

Midway through the week, I noticed my skin looking plump enough to make me wonder if it was more than just luck. The moisturiser didn’t irritate my eyes, and while it claims to help smooth fine lines around that area, I’d say the effect was subtle at best. By day seven, my skin definitely felt nourished in the morning and a bit more resilient. It wasn’t a dramatic transformation, but there was a definite uptick in smoothness. However, I wouldn’t call it a night cream game-changer.

Ultimately, the product does deliver on locking in moisture and softening the look of lines, albeit in a gentle, gradual way. Still, I don’t think I’ll be swapping out my usual night cream for Synactif. While its luxurious feel and slight boost are impressive, I’m not fully convinced it’s a must-have addition to the skincare shelf just yet.

Synactif Nighttime Moisturiser’s Main Ingredients Explained

This night cream leans heavily into hydrating and smoothing agents, with water, glycerin, and butylene glycol helping to keep skin moisturized and feeling plump. Dimethicone adds a silky texture, which explains why the cream glides on so smoothly. There’s also macadamia-derived phyto-steryl macadamiate for an extra boost of moisture, and panax ginseng root extract, which often pops up in skincare to lend revitalizing properties.

Ingredients like palm oil (and its derivatives) can be a concern for sustainability, so if that’s a priority for you, it’s worth noting here. Another point: The brand doesn’t explicitly say this formula is vegan or vegetarian. Some ingredients, such as lecithin, can come from plants or animals, and there’s no clear indication which source is used. Without confirmation, it’s hard to guarantee full vegan status, though it seems more likely to be vegetarian-friendly.

On the comedogenic front, meaning, substances that might clog pores, none of the listed ingredients are traditionally flagged as highly pore-blocking. However, everyone’s skin reacts differently, and palm oil, as well as certain butters or waxes, may still cause issues in more blemish-prone complexions. The fragrance factor is something else to keep an eye on, as some scents may lead to irritation for sensitive skin types.

Overall, this formula’s main focus is on moisture, skin softness, and subtle firming support. The wide variety of botanical extracts (like lavender oil, morus alba root extract, and melissa officinalis leaf extract) add a soothing vibe, but those with very sensitive skin may want to patch-test first. If you’re comfortable with its ingredient sources, Synactif Nighttime Moisturiser checks most of the boxes for a classic night cream by layering on a reassuringly rich and hydrating blend.

What I Liked/Didn’t Like

Here’s a quick rundown of the highlights and the areas that may need some thought before adding it to your routine:

What Works Well:

  • Silky, rich texture that feels luxurious upon application
  • Provides noticeable plumpness and locks in overnight moisture
  • Absorbs quickly without leaving a heavy or greasy film
  • Subtly softens the appearance of fine lines around the eyes
  • Leaves skin feeling comfortably hydrated by morning

What to Consider:

  • Formula contains fragrance, which may irritate very sensitive skin
  • Might not deliver dramatic results for more pronounced fine lines
  • Price point may feel high for those looking for a budget-friendly option
  • While palm oil derivatives are present for hydration, sustainability concerns may arise

My Final Thoughts

This particular night cream sits comfortably in the realm of a solid 7/10 product. It moisturizes thoroughly, feels like a gentle hug for the skin overnight, and does offer some smoothing benefits, though results might be less dramatic than the brand’s fanfare would suggest. Working it into my nightly routine for a full week felt like giving it a fair chance, especially since I’ve seen my share of night creams in the past. The bottom line is that Synactif Nighttime Moisturiser will likely charm those seeking a subtle boost of hydration and a little line-smoothing action, but those hunting for a magical, transformative formula might want to temper expectations.

In terms of audience, anyone who enjoys a richer texture and has the budget to splurge a bit could find Synactif to be a luxurious treat. The added fragrance didn’t bother me, but those with very sensitive skin might tread carefully, considering potential irritation. I’d recommend it to a friend who’s looking for that extra layer of moisture and who appreciates the Clé de Peau Beauté name, yet I’d be clear about expectations: it’s lovely, but not a life-altering must-have. Still, if you have the means to indulge, you may find yourself impressed enough to keep it on rotation.

For those looking to browse around, there are alternatives I’ve used that warrant consideration. Deascal’s Nocturnal Revive Cream is one I keep in mind for a truly dependable, covers-all-bases formula that suits pretty much all skin types, and it comes at a friendlier price point. If you want something with a bit of a different twist, BIOSSANCE’s Squalane + Ectoin Overnight Rescue is a soothing option, ideal if your skin tends to be fussy. And finally, I’ve had surprisingly good results with ELEMIS’s Pro-Collagen Overnight Matrix; it’s a more premium pick that aims to deliver a plumped, refreshed look by morning.

Before diving into any new skincare product, it’s crucial to remember a few key points. Patch-test to ensure compatibility, because even the most gentle formulas can sting someone’s skin if they’re sensitive. And as obvious as it may sound, improvements in hydration or wrinkle reduction won’t permanently stick around after a break from the cream. Consistency is key if you want to maintain the benefits. Taking all that into account, Synactif Nighttime Moisturiser could be your new bedtime companion if you’re after a touch of luxury, just know that the journey to perfect skin is never instantaneous.

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